Miami Marlins second baseman Xavier Edwards (wrist) has been scratched from Saturday's lineup against the Detroit Tigers because of discomfort in his right wrist, according to Isaac Azout of Fish On First. Edwards had been slated to lead off versus right-hander Charlie Morton. The Marlins haven't released an updated lineup yet. The speedy Edwards has played in 129 games this season and hit .280/.339/.353 with three homers, 39 RBI, a career-high 73 runs scored, and 24 stolen bases over 582 plate appearances. He has gone 7-for-34 (.206) with a homer, five RBI, five runs, and 7:4 K:BB in nine games this month.

Chicago Cubs designated hitter/outfielder Seiya Suzuki (illness) is out of the lineup on Saturday against the Tampa Bay Rays. Moises Ballesteros will serve as the Cubs' designated hitter and bat sixth versus right-hander Drew Rasmussen, while Owen Caissie will play right field and hit eighth. Suzuki is dealing with an illness that also kept him out of the Cubs' 6-4 win over the Rays on Friday. The 31-year-old has slashed .244/.324/.461 with 27 homers, 91 RBI, 69 runs scored, and five steals in 611 plate appearances, but his production has fallen off dramatically over the past couple of months. He has hit .204/.333/.269 with two HRs across 204 trips to the plate in the second half of the season.

The Chicago Cubs have recalled outfielder Owen Caissie from Triple-A Iowa, optioning outfielder Kevin Alcantara in the corresponding move. One of the organization's top prospects, Caissie had a brief run with Chicago earlier this season and slashed .208/.240/.375 with one home run and four RBI in 25 plate appearances across 11 games. He's mashed in 433 plate appearances at Triple-A, hitting .286 with a .937 OPS and 22 home runs. Caissie may have a chance for more regular playing time this go around in Chicago, with outfielder Kyle Tucker (calf) currently on the 10-day injured list. Caissie is likely battling utility man Willi Castro for playing time in right field until Tucker returns.

Philadelphia Phillies infielder Edmundo Sosa (groin) is day-to-day after leaving an 8-2 win over the Kansas City Royals on Friday with groin tightness, manager Rob Thomson told reporters. Sosa, who started at shortstop, went 0-for-3 before the team replaced him with pinch-hitter Weston Wilson in the bottom of the seventh inning. With starting shortstop Trea Turner (hamstring) on the 10-day injured list since Sept. 8, Sosa has gotten most of the playing time at the position. If Sosa is unable to go on Saturday, Bryson Stott could slide over from second base to take his place, as he did Friday. Either Wilson or Donovan Walton would fill in for Stott at second.

St. Louis Cardinals shortstop Masyn Winn (knee) is done for the year, manager Oliver Marmol announced on Friday. Winn tried to play through a torn meniscus in his right knee, but the 72-76 Cardinals will instead shut him down for the rest of 2025. Winn, who hasn't played since Monday, was in the Cardinals' initial lineup on Friday against the Milwaukee Brewers. The club made Winn a late scratch, though, replacing him with Thomas Saggese. The 23-year-old defensive stud will end his season with a .253/.310/.363 line, nine homers, 51 RBI, 72 runs, and nine steals over 537 trips to the plate. Winn is expected to undergo arthroscopic surgery sometime in the coming months. Meanwhile, both Saggese and Brendan Donovan will see time at shortstop over the final two-plus weeks of the season.

Los Angeles Dodgers catcher Will Smith (hand) is out of the starting lineup ahead of Friday's game against the San Francisco Giants. Smith will head to the bench for the second straight game and the seventh time in the last eight games. He continues to deal with right hand soreness that has lingered throughout the week. It wouldn't be shocking if Smith lands on the injured list. In his absence, Ben Rortvedt will do the catching and bat ninth against right-hander Justin Verlander on Friday. Fantasy managers should check back on Saturday to see if Smith is ready to return.

San Francisco Giants third baseman Matt Chapman's appeal of his one-game suspension was successful, and he will start at third and bat fifth on Friday night in a crucial divisional matchup against the visiting Los Angeles Dodgers and right-hander Yoshinobu Yamamoto at Oracle Park. Earlier this month, the Giants got in a little dust-up with the Colorado Rockies in which Chapman pushed Kyle Freeman. The 32-year-old will now avoid a suspension and will be available on Friday night. Chapman has gone hitless in five career at-bats against Yamamoto, but he'll also be coming into Friday's series opener in the Bay Area with a seven-game hitting streak. During his current seven-game hitting streak, Chapman has gone 11-for-24 with three home runs, three doubles, six RBI, and eight runs scored in 29 plate appearances. He has quietly produced his sixth 20-homer season in 2025.

St. Louis Cardinals shortstop Masyn Winn (knee) is starting at shortstop and will bat in the six-hole for Friday night's divisional contest against the hosting Milwaukee Brewers and right-hander Quinn Priester. Winn will return to the field on Friday after missing the last three games with a meniscus tear in his knee. While the 23-year-old will need surgery in the offseason on his knee, he plans on playing through it for the final couple of weeks of the 2025 campaign. It doesn't exactly give fantasy managers a vote of confidence, especially since he has hit .164 (11-for-67) with no home runs, a double, five RBI, nine runs, and two steals in 18 games played since Aug. 17. Winn has faced Priester only two times in his career and has two hits off of him.

Arizona Diamondbacks second baseman Ketel Marte (foot) has been scratched from the starting lineup for Friday's series opener against the Minnesota Twins. Ildemaro Vargas is now starting at the keystone and will hit second against Twins right-hander Pablo Lopez at Target Field. Marte was expected to return to action on Friday after he left Wednesday's game with a foot injury, but he apparently wasn't feeling quite 100 percent after pre-game workouts. Fantasy managers will need to remove him from their lineups and check back on Friday to see if he's able to return. Marte is a must-start second baseman in fantasy when he's active and in the lineup. Vargas, 34, is in a nice spot at the top of the order, but he'll still be a low-upside DFS streamer in Minnesota. He has gone 19-for-73 (.260) in limited action in 2025 with only three homers and 15 RBI.

The St. Louis Cardinals activated infielder Brendan Donovan (groin) from the 10-day injured list on Friday, and he's in the starting lineup for the series opener against the division-rival Milwaukee Brewers and right-hander Quinn Priester. Donovan is manning second base and will hit leadoff in his return. The 28-year-old is back on the diamond in the big leagues after missing almost a month with a strained left groin. Now that Donovan is back, he should start regularly for the Red Birds after hitting .279/.348/.402 with a .750 OPS, nine home runs, 45 RBI, 57 runs, and three steals in 110 games. Donovan is more useful in real life than in fantasy because of his lack of both power and speed as a utility man in St. Louis. With Donovan back in the fold down the stretch, young infielder Thomas Saggese will return to more of a bench role.

Milwaukee Brewers catcher William Contreras (forearm) is back behind the plate on Friday to catch right-hander Quinn Priester and will hit cleanup in the series opener against the division-rival St. Louis Cardinals and right-hander Andre Pallante at American Family Field. Contreras was hit by a pitch on his forearm on Tuesday against the Texas Rangers and was held out as a precaution on Wednesday before a team day off on Thursday. The 27-year-old backstop is now in there and will face Priester, whom he is hitting .167 against with an RBI in just six career at-bats. The Venezuelan catcher hasn't been as good as he was last year, but he should be returned to starting fantasy lineups for the weekend. Contreras has looked good so far in September, going 10-for-30 with a double, two RBI, and seven runs scored in eight games.

Todd Rosiak of the Milwaukee Journal Sentinel reports that the Brewers are reshuffling their starting rotation and will push right-hander Brandon Woodruff back to next Wednesday in a fine matchup for fantasy purposes against the Los Angeles Angels. Woodruff was originally on track to make his next start on Saturday against the division-rival St. Louis Cardinals after last pitching on Sept. 6, but they'll give him extra rest and use rookie Jacob Misiorowski on Saturday instead. It's not a big surprise after the 32-year-old Woodruff didn't make his 2025 debut until July while recovering from offseason surgery on his shoulder. He's been solid for fantasy managers upon his return, though, going 6-2 with a 3.32 ERA and 0.955 WHIP with 74 strikeouts in 59 2/3 frames over his 11 starts. Start him next week against the Halos.

The Philadelphia Phillies are placing left-handed reliever Jose Alvarado (forearm) on the 15-day injured list (retroactive to Sept. 11) on Friday with a left-forearm strain and are adding right-hander Walker Buehler to the active roster in a corresponding move, according to Matt Gelb of The Athletic. Alvarado has only appeared in 28 games out of the bullpen for the Phillies this year after serving a lengthy suspension, and now he'll miss at least the next two weeks with an injury. The 30-year-old veteran southpaw may not be able to make it back until the postseason in October. In his 26 innings of relief in his fifth year in Philly, he has a 3.81 ERA (3.60 FIP) and 1.31 WHIP with seven saves, 32 strikeouts, and seven walks. The Phillies still have a formidable bullpen, but they'll rely on lefty Matt Strahm more against lefties in a high-leverage role now.

Right-hander Michael Soroka's (shoulder) next outing will come with the Chicago Cubs, according to Andy Martinez of Watch Marquee Sports. The Cubs are ready to activate Soroka from the 15-day injured list after he threw 38 pitches over 2 1/3 innings with Triple-A Iowa on his minor-league rehab assignment on Thursday. Since Soroka isn't stretched out and the Cubs' starting rotation is currently full, he will most likely pitch in a long-relief role in his return to the Cubs. The Canadian hurler has made just one start for Chicago since they acquired him at this year's trade deadline from the Washington Nationals in late July. In his lone start for the Cubbies, he allowed a run on a solo homer with a walk and a strikeout in just two innings. Soroka has a 4.86 ERA, 1.13 WHIP, and 90:25 K:BB in 79 2/3 total innings in 2025. He can be ignored in fantasy.

Updating a previous report, Chicago Cubs outfielder Seiya Suzuki (illness) is out of the starting lineup for Friday's series opener against the visiting Tampa Bay Rays at Wrigley Field due to an illness. Willi Castro made the start in right field and is hitting eighth against Rays right-hander Shane Baz. Suzuki started in each of the team's last 12 games. It's a good time for him to rest, as he's gone 7-for-34 (.206) with no homers, two RBI, a steal, and nine strikeouts in 41 trips to the plate in nine games so far in September. There's a good chance he'll be back in there in right field for Game 2 of the series against Tampa on Saturday. The 31-year-old's recent cold spell at the plate has dropped his season slash line in 2025 to .244/.324/.461 with 27 home runs, 91 RBI, 69 runs, and five steals. The Japanese outfielder has already set career highs in homers and RBI in his fourth MLB season.

Chicago Cubs manager Craig Counsell said that right-handed reliever Daniel Palencia (shoulder) played catch at Wrigley Field on Friday, according to Andy Martinez of Watch Marquee Sports. It's a notable step for Palencia, as it's the first time the closer has thrown a ball since he suffered a strained right shoulder on Sunday. Currently on the 15-day injured list, the 25-year-old is eligible to return to the big-league bullpen on Sept. 23, but it's unclear if he'll be ready by then. Before his injury, Palencia was serving as Chicago's primary ninth-inning man while posting a 3.00 ERA, 1.18 WHIP, 59:16 K:BB, and a career-high 22 saves in 51 innings pitched. Since he landed on the shelf, Andrew Kittredge has the Cubs' only save, but veteran Brad Keller could also factor into the short-term saves picture.

Chicago Cubs outfielder Kyle Tucker (calf) is hitting and throwing, but he will not begin running until after the weekend and is "unlikely" to come off the 10-day injured list when he's eligible on Tuesday, according to manager Craig Counsell. Tucker is making progress from a left-calf strain, but he won't return early next week for fantasy managers. The Cubs will be pretty careful with the 28-year-old All-Star, but barring a setback, he should be back with Chicago before the end of September. With Tucker out lately, the Cubs have been mixing and matching in right field with Seiya Suzuki and Willi Castro. Tucker went through a little slump at the plate last month, but had bounced back nicely right before injuring his calf. When he's healthy and back with the Cubs, the former first-rounder will be a must-start in all fantasy lineups.

Arizona Diamondbacks second baseman Ketel Marte (foot) is scheduled to be in the starting lineup for Friday's series opener against the Minnesota Twins, according to John Gambadoro of Arizona Sports. The Diamondbacks will see how Marte is feeling when he comes in before the game. Marte is hitting .171 (6-for-35) in a small sample size so far in September and left Wednesday's game early against the San Francisco Giants with a right-foot bruise. Thankfully, X-rays were negative, and the 31-year-old All-Star should be back in there on Friday. Fantasy managers will want to make sure Marte isn't scratched just before first pitch, and they'll also be hoping he can turn it around at the plate against Twins right-hander Pablo Lopez on Friday. He's gone 1-for-3 with an RBI in his career against Lopez.

Chicago Cubs third baseman Matt Shaw is back in the lineup on Friday against Tampa Bay Rays right-hander Shane Baz. He'll play third base and bat ninth. Shaw was scratched from the lineup for the Cubs' 3-2 win over the Atlanta Braves on Wednesday while dealing with a personal matter, though he did pinch hit. After a productive August (.839 OPS, five home runs, 10 RBI), Shaw has slumped in his first nine games this month. He's 5-for-24 (.208) with a double, four RBI, eight strikeouts, and four walks. Overall, the 23-year-old rookie has batted .226/.292/.388 with 11 homers, 39 RBI, 47 runs, and 16 steals in 383 plate appearances.

Chicago Cubs designated hitter/outfielder Seiya Suzuki is out of the lineup on Friday against Tampa Bay Rays right-hander Shane Baz. Moises Ballesteros will take over as the DH and bat sixth. Suzuki is getting the day off amid a severe slump. He has just one home run since the All-Star break and has opened September 7-for-34 (.206) with no extra-base hits, two RBI, nine strikeouts, and six walks in nine games. Thanks to his excellent production over the first couple months of the season, the 31-year-old still boasts a strong .244/.324/.461 line with 27 homers, 91 RBI, 69 runs, and five stolen bases over 611 plate appearances.