| Date | Status | Player | Injury | Target Return? | Prognosis |
|---|
| 2025-09-24 | 10-day | Bo Bichette | Unspecified | 2025-10-04 | The Blue Jays placed Bo Bichette on the 10-day injured list. |
| 2025-09-24 | 10-day | Luis Robert Jr. | Unspecified | 2025-10-04 | The White Sox placed Luis Robert Jr. on the 10-day injured list. |
| 2025-09-24 | 10-day | Matt Vierling | Unspecified | 2025-10-04 | The Tigers placed Matt Vierling on the 10-day injured list. |
| 2025-09-24 | 10-day | Jonathan Aranda | Unspecified | 2025-10-04 | The Rays placed Jonathan Aranda on the 10-day injured list. |
| 2025-09-24 | 10-day | Lane Thomas | Unspecified | 2025-10-04 | The Guardians placed Lane Thomas on the 10-day injured list. |
| 2025-09-24 | 10-day | Roman Anthony | Unspecified | 2025-10-04 | The Red Sox placed Roman Anthony on the 10-day injured list. |
| 2025-09-24 | 10-day | Denzel Clarke | Unspecified | 2025-10-04 | The Athletics placed Denzel Clarke on the 10-day injured list. |
| 2025-09-24 | 10-day | Corey Seager | Unspecified | 2025-10-04 | The Rangers placed Corey Seager on the 10-day injured list. |
| 2025-09-24 | 10-day | Marcus Semien | Unspecified | 2025-10-04 | The Rangers placed Marcus Semien on the 10-day injured list. |
| 2025-09-24 | 10-day | Sam Haggerty | Unspecified | 2025-10-04 | The Rangers placed Sam Haggerty on the 10-day injured list. |
| 2025-09-24 | 10-day | Zach Neto | Unspecified | 2025-10-04 | The Angels placed Zach Neto on the 10-day injured list. |
| 2025-09-24 | 10-day | Kyle Isbel | Unspecified | 2025-10-04 | The Royals placed Kyle Isbel on the 10-day injured list. |
| 2025-09-24 | 10-day | Yordan Alvarez | Unspecified | 2025-10-04 | The Astros placed Yordan Alvarez on the 10-day injured list. |
| 2025-09-24 | 10-day | Matt Wallner | Unspecified | 2025-10-04 | The Twins placed Matt Wallner on the 10-day injured list. |
| 2025-09-24 | 10-day | Colt Keith | Unspecified | 2025-10-04 | The Tigers placed Colt Keith on the 10-day injured list. |
| 2025-09-24 | 10-day | Nolan Jones | Unspecified | 2025-10-04 | The Guardians placed Nolan Jones on the 10-day injured list. |
| 2025-09-24 | 10-day | Zack Gelof | Unspecified | 2025-10-04 | The Athletics placed Zack Gelof on the 10-day injured list. |
| 2025-09-24 | 10-day | Andrew Benintendi | Unspecified | 2025-10-04 | The White Sox placed Andrew Benintendi on the 10-day injured list. |
| 2025-09-24 | 10-day | Ty France | Unspecified | 2025-10-04 | The Blue Jays placed Ty France on the 10-day injured list. |
| 2025-09-24 | 10-day | Dustin Harris | Unspecified | 2025-10-04 | The Rangers placed Dustin Harris on the 10-day injured list. |
| 2025-09-24 | 15-day | Albert Suárez | Unspecified | 2025-10-09 | The Orioles placed Albert Suárez on the 15-day injured list. |
| 2025-09-24 | 15-day | Brent Headrick | Unspecified | 2025-10-09 | The Yankees placed Brent Headrick on the 15-day injured list. |
| 2025-09-24 | 15-day | Jonathan Loáisiga | Unspecified | 2025-10-09 | The Yankees placed Jonathan Loáisiga on the 15-day injured list. |
| 2025-09-24 | 15-day | Logan Evans | Unspecified | 2025-10-09 | The Mariners placed Logan Evans on the 15-day injured list. |
| 2025-09-24 | 15-day | Jackson Kowar | Unspecified | 2025-10-09 | The Mariners placed Jackson Kowar on the 15-day injured list. |
| 2025-09-24 | 15-day | Bryan Hudson | Unspecified | 2025-10-09 | The White Sox placed Bryan Hudson on the 15-day injured list. |
| 2025-09-24 | 15-day | Elvis Peguero | Unspecified | 2025-10-09 | The White Sox placed Elvis Peguero on the 15-day injured list. |
| 2025-09-24 | 15-day | Sawyer Gipson-Long | Unspecified | 2025-10-09 | The Tigers placed Sawyer Gipson-Long on the 15-day injured list. |
| 2025-09-24 | 15-day | Mason Englert | Unspecified | 2025-10-09 | The Rays placed Mason Englert on the 15-day injured list. |
| 2025-09-24 | 15-day | Nic Enright | Unspecified | 2025-10-09 | The Guardians placed Nic Enright on the 15-day injured list. |
| 2025-09-24 | 15-day | Bailey Falter | Unspecified | 2025-10-09 | The Royals placed Bailey Falter on the 15-day injured list. |
| 2025-09-24 | 15-day | Hunter Harvey | Unspecified | 2025-10-09 | The Royals placed Hunter Harvey on the 15-day injured list. |
| 2025-09-24 | 15-day | Seth Lugo | Unspecified | 2025-10-09 | The Royals placed Seth Lugo on the 15-day injured list. |
| 2025-09-24 | 15-day | Spencer Arrighetti | Unspecified | 2025-10-09 | The Astros placed Spencer Arrighetti on the 15-day injured list. |
| 2025-09-24 | 15-day | Josh Hader | Unspecified | 2025-10-09 | The Astros placed Josh Hader on the 15-day injured list. |
| 2025-09-24 | 15-day | Lance McCullers Jr. | Unspecified | 2025-10-09 | The Astros placed Lance McCullers Jr. on the 15-day injured list. |
| 2025-09-24 | 15-day | Bennett Sousa | Unspecified | 2025-10-09 | The Astros placed Bennett Sousa on the 15-day injured list. |
| 2025-09-24 | 15-day | Brennan Bernardino | Unspecified | 2025-10-09 | The Red Sox placed Brennan Bernardino on the 15-day injured list. |
| 2025-09-24 | 15-day | Richard Fitts | Unspecified | 2025-10-09 | The Red Sox placed Richard Fitts on the 15-day injured list. |
| 2025-09-24 | 15-day | Jordan Hicks | Unspecified | 2025-10-09 | The Red Sox placed Jordan Hicks on the 15-day injured list. |
| 2025-09-24 | 15-day | Dustin May | Unspecified | 2025-10-09 | The Red Sox placed Dustin May on the 15-day injured list. |
| 2025-09-24 | 15-day | Joey Estes | Unspecified | 2025-10-09 | The Athletics placed Joey Estes on the 15-day injured list. |
| 2025-09-24 | 15-day | Jacob Lopez | Unspecified | 2025-10-09 | The Athletics placed Jacob Lopez on the 15-day injured list. |
| 2025-09-24 | 15-day | Jack Perkins | Unspecified | 2025-10-09 | The Athletics placed Jack Perkins on the 15-day injured list. |
| 2025-09-24 | 15-day | Tyler Anderson | Unspecified | 2025-10-09 | The Angels placed Tyler Anderson on the 15-day injured list. |
| 2025-09-24 | 15-day | Andrew Chafin | Unspecified | 2025-10-09 | The Angels placed Andrew Chafin on the 15-day injured list. |
| 2025-09-24 | 15-day | David Festa | Unspecified | 2025-10-09 | The Twins placed David Festa on the 15-day injured list. |
| 2025-09-24 | 15-day | Anthony Misiewicz | Unspecified | 2025-10-09 | The Twins placed Anthony Misiewicz on the 15-day injured list. |
| 2025-09-24 | 15-day | Justin Topa | Unspecified | 2025-10-09 | The Twins placed Justin Topa on the 15-day injured list. |
| 2025-09-24 | 15-day | Shawn Dubin | Unspecified | 2025-10-09 | The Orioles placed Shawn Dubin on the 15-day injured list. |
| 2025-09-24 | 15-day | Nathan Eovaldi | Unspecified | 2025-10-09 | The Rangers placed Nathan Eovaldi on the 15-day injured list. |
| 2025-09-24 | 15-day | Ryan Bergert | Unspecified | 2025-10-09 | The Royals placed Ryan Bergert on the 15-day injured list. |
| 2025-09-24 | 15-day | José Soriano | Unspecified | 2025-10-09 | The Angels placed José Soriano on the 15-day injured list. |
| 2025-09-24 | 15-day | Lucas Erceg | Unspecified | 2025-10-09 | The Royals placed Lucas Erceg on the 15-day injured list. |
| 2025-09-24 | 15-day | Martín Pérez | Unspecified | 2025-10-09 | The White Sox placed Martín Pérez on the 15-day injured list. |
| 2025-09-24 | 15-day | Chris Bassitt | Unspecified | 2025-10-09 | The Blue Jays placed Chris Bassitt on the 15-day injured list. |
| 2025-09-24 | 15-day | Sean Newcomb | Unspecified | 2025-10-09 | The Athletics placed Sean Newcomb on the 15-day injured list. |
| 2025-09-24 | 15-day | Robert Stephenson | Unspecified | 2025-10-09 | The Angels placed Robert Stephenson on the 15-day injured list. |
| 2025-09-24 | 15-day | Pablo López | Unspecified | 2025-10-09 | The Twins placed Pablo López on the 15-day injured list. |
| 2025-09-24 | 15-day | Chayce McDermott | Unspecified | 2025-10-09 | The Orioles placed Chayce McDermott on the 15-day injured list. |
| 2025-09-24 | 60-day | Brendan Rodgers | Unspecified | 2025-11-23 | The Astros placed Brendan Rodgers on the 60-day injured list. |
| 2025-09-24 | 60-day | Zach Dezenzo | Unspecified | 2025-11-23 | The Astros placed Zach Dezenzo on the 60-day injured list. |
| 2025-09-24 | 60-day | Pedro León | Unspecified | 2025-11-23 | The Astros placed Pedro León on the 60-day injured list. |
| 2025-09-24 | 60-day | Gerrit Cole | Unspecified | 2025-11-23 | The Yankees placed Gerrit Cole on the 60-day injured list. |
| 2025-09-24 | 60-day | Jake Cousins | Unspecified | 2025-11-23 | The Yankees placed Jake Cousins on the 60-day injured list. |
| 2025-09-24 | 60-day | Clarke Schmidt | Unspecified | 2025-11-23 | The Yankees placed Clarke Schmidt on the 60-day injured list. |
| 2025-09-24 | 60-day | Oswaldo Cabrera | Unspecified | 2025-11-23 | The Yankees placed Oswaldo Cabrera on the 60-day injured list. |
| 2025-09-24 | 60-day | Angel Bastardo | Unspecified | 2025-11-23 | The Blue Jays placed Angel Bastardo on the 60-day injured list. |
| 2025-09-24 | 60-day | Ryan Burr | Unspecified | 2025-11-23 | The Blue Jays placed Ryan Burr on the 60-day injured list. |
| 2025-09-24 | 60-day | Bowden Francis | Unspecified | 2025-11-23 | The Blue Jays placed Bowden Francis on the 60-day injured list. |
| 2025-09-24 | 60-day | Yimi García | Unspecified | 2025-11-23 | The Blue Jays placed Yimi García on the 60-day injured list. |
| 2025-09-24 | 60-day | Robinson Piña | Unspecified | 2025-11-23 | The Blue Jays placed Robinson Piña on the 60-day injured list. |
| 2025-09-24 | 60-day | Nick Sandlin | Unspecified | 2025-11-23 | The Blue Jays placed Nick Sandlin on the 60-day injured list. |
| 2025-09-24 | 60-day | Gregory Santos | Unspecified | 2025-11-23 | The Mariners placed Gregory Santos on the 60-day injured list. |
| 2025-09-24 | 60-day | Trent Thornton | Unspecified | 2025-11-23 | The Mariners placed Trent Thornton on the 60-day injured list. |
| 2025-09-24 | 60-day | Ryan Bliss | Unspecified | 2025-11-23 | The Mariners placed Ryan Bliss on the 60-day injured list. |
| 2025-09-24 | 60-day | Prelander Berroa | Unspecified | 2025-11-23 | The White Sox placed Prelander Berroa on the 60-day injured list. |
| 2025-09-24 | 60-day | Ky Bush | Unspecified | 2025-11-23 | The White Sox placed Ky Bush on the 60-day injured list. |
| 2025-09-24 | 60-day | Miguel Castro | Unspecified | 2025-11-23 | The White Sox placed Miguel Castro on the 60-day injured list. |
| 2025-09-24 | 60-day | Drew Thorpe | Unspecified | 2025-11-23 | The White Sox placed Drew Thorpe on the 60-day injured list. |
| 2025-09-24 | 60-day | Beau Brieske | Unspecified | 2025-11-23 | The Tigers placed Beau Brieske on the 60-day injured list. |
| 2025-09-24 | 60-day | Alex Cobb | Unspecified | 2025-11-23 | The Tigers placed Alex Cobb on the 60-day injured list. |
| 2025-09-24 | 60-day | Jason Foley | Unspecified | 2025-11-23 | The Tigers placed Jason Foley on the 60-day injured list. |
| 2025-09-24 | 60-day | Sean Guenther | Unspecified | 2025-11-23 | The Tigers placed Sean Guenther on the 60-day injured list. |
| 2025-09-24 | 60-day | Jackson Jobe | Unspecified | 2025-11-23 | The Tigers placed Jackson Jobe on the 60-day injured list. |
| 2025-09-24 | 60-day | Ty Madden | Unspecified | 2025-11-23 | The Tigers placed Ty Madden on the 60-day injured list. |
| 2025-09-24 | 60-day | Reese Olson | Unspecified | 2025-11-23 | The Tigers placed Reese Olson on the 60-day injured list. |
| 2025-09-24 | 60-day | Hunter Bigge | Unspecified | 2025-11-23 | The Rays placed Hunter Bigge on the 60-day injured list. |
| 2025-09-24 | 60-day | Alex Faedo | Unspecified | 2025-11-23 | The Rays placed Alex Faedo on the 60-day injured list. |
| 2025-09-24 | 60-day | Nate Lavender | Unspecified | 2025-11-23 | The Rays placed Nate Lavender on the 60-day injured list. |
| 2025-09-24 | 60-day | Shane McClanahan | Unspecified | 2025-11-23 | The Rays placed Shane McClanahan on the 60-day injured list. |
| 2025-09-24 | 60-day | Manuel Rodríguez | Unspecified | 2025-11-23 | The Rays placed Manuel Rodríguez on the 60-day injured list. |
| 2025-09-24 | 60-day | Brian Van Belle | Unspecified | 2025-11-23 | The Rays placed Brian Van Belle on the 60-day injured list. |
| 2025-09-24 | 60-day | Taylor Walls | Unspecified | 2025-11-23 | The Rays placed Taylor Walls on the 10-day injured list. |
| 2025-09-24 | 60-day | Jonny DeLuca | Unspecified | 2025-11-23 | The Rays placed Jonny DeLuca on the 60-day injured list. |
| 2025-09-24 | 60-day | Stuart Fairchild | Unspecified | 2025-11-23 | The Rays placed Stuart Fairchild on the 60-day injured list. |
| 2025-09-24 | 60-day | Sam Hentges | Unspecified | 2025-11-23 | The Guardians placed Sam Hentges on the 60-day injured list. |
| 2025-09-24 | 60-day | Ben Lively | Unspecified | 2025-11-23 | The Guardians placed Ben Lively on the 60-day injured list. |
| 2025-09-24 | 60-day | John Means | Unspecified | 2025-11-23 | The Guardians placed John Means on the 60-day injured list. |
| 2025-09-24 | 60-day | Andrew Walters | Unspecified | 2025-11-23 | The Guardians placed Andrew Walters on the 60-day injured list. |
| 2025-09-24 | 60-day | Will Brennan | Unspecified | 2025-11-23 | The Guardians placed Will Brennan on the 60-day injured list. |
| 2025-09-24 | 60-day | Marcelo Mayer | Unspecified | 2025-11-23 | The Red Sox placed Marcelo Mayer on the 60-day injured list. |
| 2025-09-24 | 60-day | Kris Bubic | Unspecified | 2025-11-23 | The Royals placed Kris Bubic on the 60-day injured list. |
| 2025-09-24 | 60-day | Alec Marsh | Unspecified | 2025-11-23 | The Royals placed Alec Marsh on the 60-day injured list. |
| 2025-09-24 | 60-day | James McArthur | Unspecified | 2025-11-23 | The Royals placed James McArthur on the 60-day injured list. |
| 2025-09-24 | 60-day | Ronel Blanco | Unspecified | 2025-11-23 | The Astros placed Ronel Blanco on the 60-day injured list. |
| 2025-09-24 | 60-day | Luis Garcia | Unspecified | 2025-11-23 | The Astros placed Luis Garcia on the 60-day injured list. |
| 2025-09-24 | 60-day | Kaleb Ort | Unspecified | 2025-11-23 | The Astros placed Kaleb Ort on the 15-day injured list. |
| 2025-09-24 | 60-day | John Rooney | Unspecified | 2025-11-23 | The Astros placed John Rooney on the 60-day injured list. |
| 2025-09-24 | 60-day | Brandon Walter | Unspecified | 2025-11-23 | The Astros placed Brandon Walter on the 60-day injured list. |
| 2025-09-24 | 60-day | Hayden Wesneski | Unspecified | 2025-11-23 | The Astros placed Hayden Wesneski on the 60-day injured list. |
| 2025-09-24 | 60-day | Vaughn Grissom | Unspecified | 2025-11-23 | The Red Sox placed Vaughn Grissom on the 60-day injured list. |
| 2025-09-24 | 60-day | Anthony Rendon | Unspecified | 2025-11-23 | The Angels placed Anthony Rendon on the 60-day injured list. |
| 2025-09-24 | 60-day | Gustavo Campero | Unspecified | 2025-11-23 | The Angels placed Gustavo Campero on the 60-day injured list. |
| 2025-09-24 | 60-day | Jorge Soler | Unspecified | 2025-11-23 | The Angels placed Jorge Soler on the 60-day injured list. |
| 2025-09-24 | 60-day | Kutter Crawford | Unspecified | 2025-11-23 | The Red Sox placed Kutter Crawford on the 60-day injured list. |
| 2025-09-24 | 60-day | Hunter Dobbins | Unspecified | 2025-11-23 | The Red Sox placed Hunter Dobbins on the 60-day injured list. |
| 2025-09-24 | 60-day | Luis Guerrero | Unspecified | 2025-11-23 | The Red Sox placed Luis Guerrero on the 60-day injured list. |
| 2025-09-24 | 60-day | Liam Hendriks | Unspecified | 2025-11-23 | The Red Sox placed Liam Hendriks on the 60-day injured list. |
| 2025-09-24 | 60-day | Tanner Houck | Unspecified | 2025-11-23 | The Red Sox placed Tanner Houck on the 60-day injured list. |
| 2025-09-24 | 60-day | Patrick Sandoval | Unspecified | 2025-11-23 | The Red Sox placed Patrick Sandoval on the 60-day injured list. |
| 2025-09-24 | 60-day | Josh Winckowski | Unspecified | 2025-11-23 | The Red Sox placed Josh Winckowski on the 60-day injured list. |
| 2025-09-24 | 60-day | Triston Casas | Unspecified | 2025-11-23 | The Red Sox placed Triston Casas on the 60-day injured list. |
| 2025-09-24 | 60-day | Ben Bowden | Unspecified | 2025-11-23 | The Athletics placed Ben Bowden on the 60-day injured list. |
| 2025-09-24 | 60-day | Gunnar Hoglund | Unspecified | 2025-11-23 | The Athletics placed Gunnar Hoglund on the 60-day injured list. |
| 2025-09-24 | 60-day | Grant Holman | Unspecified | 2025-11-23 | The Athletics placed Grant Holman on the 60-day injured list. |
| 2025-09-24 | 60-day | José Leclerc | Unspecified | 2025-11-23 | The Athletics placed José Leclerc on the 60-day injured list. |
| 2025-09-24 | 60-day | Luis Medina | Unspecified | 2025-11-23 | The Athletics placed Luis Medina on the 60-day injured list. |
| 2025-09-24 | 60-day | Austin Wynns | Unspecified | 2025-11-23 | The Athletics placed Austin Wynns on the 60-day injured list. |
| 2025-09-24 | 60-day | Reid Detmers | Unspecified | 2025-11-23 | The Angels placed Reid Detmers on the 60-day injured list. |
| 2025-09-24 | 60-day | Carson Fulmer | Unspecified | 2025-11-23 | The Angels placed Carson Fulmer on the 60-day injured list. |
| 2025-09-24 | 60-day | Ben Joyce | Unspecified | 2025-11-23 | The Angels placed Ben Joyce on the 60-day injured list. |
| 2025-09-24 | 60-day | Victor Mederos | Unspecified | 2025-11-23 | The Angels placed Victor Mederos on the 60-day injured list. |
| 2025-09-24 | 60-day | Hunter Strickland | Unspecified | 2025-11-23 | The Angels placed Hunter Strickland on the 60-day injured list. |
| 2025-09-24 | 60-day | Josh Sborz | Unspecified | 2025-11-23 | The Rangers placed Josh Sborz on the 60-day injured list. |
| 2025-09-24 | 60-day | Evan Carter | Unspecified | 2025-11-23 | The Rangers placed Evan Carter on the 60-day injured list. |
| 2025-09-24 | 60-day | Alan Roden | Unspecified | 2025-11-23 | The Twins placed Alan Roden on the 60-day injured list. |
| 2025-09-24 | 60-day | Félix Bautista | Unspecified | 2025-11-23 | The Orioles placed Félix Bautista on the 60-day injured list. |
| 2025-09-24 | 60-day | Zach Eflin | Unspecified | 2025-11-23 | The Orioles placed Zach Eflin on the 60-day injured list. |
| 2025-09-24 | 60-day | Grayson Rodriguez | Unspecified | 2025-11-23 | The Orioles placed Grayson Rodriguez on the 60-day injured list. |
| 2025-09-24 | 60-day | Brandon Young | Unspecified | 2025-11-23 | The Orioles placed Brandon Young on the 60-day injured list. |
| 2025-09-24 | 60-day | Gary Sánchez | Unspecified | 2025-11-23 | The Orioles placed Gary Sánchez on the 60-day injured list. |
| 2025-09-24 | 60-day | Cody Bradford | Unspecified | 2025-11-23 | The Rangers placed Cody Bradford on the 60-day injured list. |
| 2025-09-24 | 60-day | Jon Gray | Unspecified | 2025-11-23 | The Rangers placed Jon Gray on the 60-day injured list. |
| 2025-09-24 | 7-day | Travis d'Arnaud | Unspecified | 2025-10-01 | The Angels placed Travis d'Arnaud on the 7-day injured list. |
| 2025-09-23 | 15-day | Ryan Zeferjahn | Unspecified | 2025-10-08 | The Angels placed Ryan Zeferjahn on the 15-day injured list. |
| 2025-09-23 | 15-day | Colin Selby | Unspecified | 2025-10-08 | The Orioles placed Colin Selby on the 15-day injured list. |
| 2025-09-23 | 60-day | Anthony Santander | Unspecified | 2025-11-22 | The Blue Jays placed Anthony Santander on the 60-day injured list. |
| 2025-09-23 | 7-day | Ryan Jeffers | Unspecified | 2025-09-30 | The Twins placed Ryan Jeffers on the 7-day injured list. |
| 2025-09-22 | 10-day | Christian Vázquez | Unspecified | 2025-10-02 | The Twins placed Christian Vázquez on the 10-day injured list. |
| 2025-09-22 | 10-day | Adley Rutschman | Unspecified | 2025-10-02 | The Orioles placed Adley Rutschman on the 10-day injured list. |
| 2025-09-21 | 10-day | Wilyer Abreu | Unspecified | 2025-10-01 | The Red Sox placed Wilyer Abreu on the 10-day injured list. |
| 2025-09-20 | 10-day | Max Muncy | Unspecified | 2025-09-30 | The Athletics placed Max Muncy on the 10-day injured list. |
| 2025-09-20 | 15-day | Owen White | Unspecified | 2025-10-05 | The White Sox placed Owen White on the 15-day injured list. |
| 2025-09-19 | 10-day | Nolan Schanuel | Unspecified | 2025-09-29 | The Angels placed Nolan Schanuel on the 10-day injured list. |
| 2025-09-19 | 15-day | Kyle Finnegan | Unspecified | 2025-10-04 | The Tigers placed Kyle Finnegan on the 15-day injured list. |
| 2025-09-19 | 15-day | Steven Cruz | Unspecified | 2025-10-04 | The Royals placed Steven Cruz on the 15-day injured list. |
| 2025-09-19 | 60-day | Isaac Paredes | Unspecified | 2025-11-18 | The Astros placed Isaac Paredes on the 60-day injured list. |
| 2025-09-19 | 60-day | Tyler Mahle | Unspecified | 2025-11-18 | The Rangers placed Tyler Mahle on the 60-day injured list. |
| 2025-09-19 | 60-day | Scott Blewett | Unspecified | 2025-11-18 | The Orioles placed Scott Blewett on the 60-day injured list. |
| 2025-09-18 | 60-day | Paul Sewald | Unspecified | 2025-11-17 | The Tigers placed Paul Sewald on the 60-day injured list. |
| 2025-09-17 | 60-day | Cole Ragans | Unspecified | 2025-11-16 | The Royals placed Cole Ragans on the 60-day injured list. |
| 2025-09-16 | 10-day | Jordan Westburg | Unspecified | 2025-09-26 | The Orioles placed Jordan Westburg on the 10-day injured list. |
| 2025-09-16 | 15-day | Danny Coulombe | Unspecified | 2025-10-01 | The Rangers placed Danny Coulombe on the 15-day injured list. |
| 2025-09-16 | 7-day | Michael Wacha | Unspecified | 2025-09-23 | The Royals placed Michael Wacha on the 7-day injured list. |
| 2025-09-15 | 7-day | Logan O'Hoppe | Unspecified | 2025-09-22 | The Angels placed Logan O'Hoppe on the 7-day injured list. |